ISA is of secondary importance to performance, barring any really bad features (x87).
The x86 architecture has smoothed over some very significant shortcomings that could not be fully worked around by hardware.
However, the credit for being competitive at all rests more on the some of best semiconductor manufacturing in the world, and more engineering effort than any other architecture ever had.
Making x86 competitive did not come cheap, and just as there is no massive technical disadvantage to x86, the upside to having it is similarly limited.
The price tag for the same results is going to be higher, and there is less flexibility to push redesigns and shrinks, since those would be at the mercy of another company.
The x86 architecture has smoothed over some very significant shortcomings that could not be fully worked around by hardware.
However, the credit for being competitive at all rests more on the some of best semiconductor manufacturing in the world, and more engineering effort than any other architecture ever had.
Making x86 competitive did not come cheap, and just as there is no massive technical disadvantage to x86, the upside to having it is similarly limited.
The price tag for the same results is going to be higher, and there is less flexibility to push redesigns and shrinks, since those would be at the mercy of another company.