There never was a good reason to go with the RGB choice other than being a loser to the antagonist and having no choice, peaceful coexistence was possible.
I prefer to imagine everything ended at the Anderson & Shepard scene.
I suppose even with the destroy ending, nothing stops organics from recreating A.I. ?You misunderstand, if there is AI in Andromeda the ME3 ending becomes recontextualized.
Not sure what you're getting at. (derp dumb as the ending was haha)