Personally I encountered several bugs:
1. Mouse problem (apparently the highlighted item is not necessarily what you are currently pointing at)
2. In at least two quest where I got quest items before getting the quest and the quests do not advance to the proper stages (one of them is particularly bad as it involves an important equipment so I have to use console command to set the proper stage)
3. Crash to desktop after changing location (rare, and fortunately it always happened after an auto-save)
4. Some items are not properly stacked in the equipment list (e.g. some "Lesser Soul Gems" may appear as ten individual entries instead of "Lesser Soul Gems (10)")
5. Sometimes one can equip two amulets/necklaces at the same time.
The mouse problem is the most serious one and I really hope they fix it in the next patch.
What I hope they add in the next patch:
1. A proper character sheet. It's not good to have add "improve Magicka regeneration" from all items by one's own. The active effects list should display effects AND items at the same time, instead of current "showing item only when selecting an effect" design. Also, it'd be nice to know if you have any slot without item equipped.
2. The ability to set up equipment sets will be very useful. Current "number key" system is only good enough for selecting from different spells or weapons. It'd be much better to be able to push "1" to equip all "improve Alchemy" items before making potions, "2" to equip all magic resistant armors, "3" to equip all "improve Speech/price" items before trading, etc.
3. There should be an easy way to tell which enchantments you already learned. Only able to see a list of learned enchantments at an enchanting table is, well, not perfect, especially considering this game does not have an built-in notebook. Additional point: when buying spell tomes, it should display whether you already learned this spell or not, for convenience.
4. The perk display, although quite fancy, also could use some improvements. At least, a list of all effects from learned perks, and a list of all "qualified but not learned" perks, would be a nice addition
5. The ability to call your horse, even only with short distances, would be welcome. Sometimes the horse flee to a pretty distant location and it can take quite some time to find it in a dense forest.