Bouncing Zabaglione Bros.
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Well, even if they're uncorrelated, purely by chance a significant fraction of them will be clustered.
You've got no idea if they will be clustered in the middle of a chip, or at a point where the corners of four chips meet, thus taking out all four chips. It might also be the case that a cluster can destroy a chip or two, where those same defects spread over a larger area will allow parts of a chip to be fused off to still become a viable product.
Over a large enough sample of wafers, it probably all evens out anyway, and the defect rate averages out to approximately the same number of defects per wafer regardless of whether an individual wafer has it's defects all spread out or in clusters. This of course assumes that defects are random, and not influenced by other factors.