In my case my max refresh rate is 175hz. On the desktop that's perfectly fine, but in games that don't play well with refresh rates not being evenly divisible by 2 to 4, you get stutters and hitches. Not to mention certain games just simply work better at 120hz or 60hz. Many games and many engines have their quirks, and sometimes you have to fiddle with a mixture of settings to get things right. Being able to have my desktop refresh rate always at 175hz, or at least 160hz, but then switch to 144hz, 120hz, or 60hz independently for each game driver profile, would be a very welcome capability.
Same goes for DSR. My screen is 3840x1600 ultrawide. Some (or even many) games will only go up to 2560x1440 16:9 as selectable in the menu. I would like the ability to add higher DSR resolutions (in my case typically 5120x2160, 5760x2400, or 7680x3200) on a per game basis in the driver profile because some games simply require the desktop to be set at that resolution to have the ability to select the resolution.
It's not the end of the world or anything.. All I'm saying is that it would be nice to have.