DavidGraham
Veteran
Yep, Windows 10 will continue to work even if you changed the motherboard + CPU + GPU, my friend had an old Phenom II CPU + an old HD 5870 card, he switched to a Ryzen 3000 + 6700 XT, and Windows continued to work flawlessly.You haven't had to do clean OS installs on motherboard changes for a long time. At least with Windows.