Frankly, Who knows? Who knows what those games would have been if the dev had made them primarily for PCs that can run Crysis like games at High(or Very High). Maybe the crowd simulations, AI behaviours, number of stuff on screen would have been completely different !
I think this is a moot argument: what can you potentially do if you use the world's most powerful super computer to make a game? A game that nobody can play.
The way I see it is that I'd be happy to work on something that potentially millions of players can play, and I'd love this something to be the 'best' (insert your favourite definition of best) on that platform. It gives me more pleasure than trying to display hundreds of characters on a super computer.