Yup, with today's performance scaling, it's almost always a sure bet that the single card will perform better. But before making the final purchase, it's always a good idea to double-check with reviews.
Note that SLI works pretty well in the majority of performance-intensive games today. For games in which it doesn't work, it just means you won't see any benefit from running in SLI mode. You don't actually have to do anything about it, you just won't see any difference between enabling or disabling SLI.
The only drawback to running in SLI mode is that you can only get output from a single display.
When building an SLI system, it is also important to consider whether or not your current hardware is up to the task. The power supply and motherboard are critical when upgrading to SLI, and if you would need a new one (though that is unlikely with $150 boards, as those are usually pretty low in power consumption), then be sure to factor that into the cost of the upgrade.