Installed and patched NWN2 last night and was only getting software sound options (Miles 2D FTW!). Why didn't you people tell me I had to manually add games in Alchemy's little front-end? Wasted five minutes of my life figuring this out, so someone owes me.
It's a lot easier just copying and pasting the two files (dsound.dll and dsound.ini) into the game's directory. I don't even use the ALchemy front-end.