OK one of the better extreme OC'ers has gone to town with the 480.
They managed to hit 1500MHz, the caveat being and they said this "it is not a 24/7 setting", this brought it up to the performance of a 980 (not a reference model).
Enjoy the video, just appreciate English is not his first language.
And to hit that 1500MHz, yeah quite a lot of DIY modding required including software accessing the PWM controller - his changes are well outside of 'normal' operating parameters but this is extreme OC.
Also to stress, he mentions the PCIe slot being OK, but what he focused on was the ATX12V 24-pin and not the actual x16 slot, so yeah its potential for being an issue still applies.
Cheers