Mass Effect is a good game, but its not great. It's no KOTOR, not even close. The characters are not as good, there is very little humor, the uncharted worlds are boring, and the core worlds are too short. It feels like it needed another 6 solid months of content creation. Each of the core plot planets can be finished in a couple of hours, loot and character development are simplified. No cities at all beside the Citadel (ok Noveria maybe but its still too small), and the game often recycles the same generic rooms and corridors on many of the random pointless planets. KOTOR had so much more core content, every major planet had a city/base, the game took at least 30-40hrs to finish and none of it was generic or boring or repetitive. If you skip the UCWs in Mass Effect (which you probably will once you see how boring they are or you get insta-killed when the giant worm spawns right under the mako) it can be finished in less than 10hrs. The control scheme baffles me, you have 2 buttons to draw/holster gun but only one spell hotkey, sprint is the same as use (this will drive you crazy), first aid takes up a face button when it could easily be on the wheel, and grenade is the damn back button. No option to change the binds, I would like to have a chat with the person who thought up this scheme. Motion blur activates even when you are barely moving the camera at all (to cover up the often terrible framerate no doubt) making everything a fuzzy mess and giving me a headache, good think you can disable it or I would have taken the game right back to the store.
However the story is pretty good and I really love the combat system. Powerful yet simple, and a blast to play with Vanguard. That's probably why I started a new game on Hardcore as soon as I finished my first run (veteran is too easy), just cant get enough of the combat (singularity vanguard is a beast) and I want to see the alternate endings. I cant help but wish for KOTOR with this combat system, but I am optimistic for the sequel (less style more substance please).