They can probably scale this design down to mainstream parts, like they've always done.
Obviously they're showing the big guns to the press (just like they showed the 8800 at launch, but there was an 8600 available not much later, basically just G80 scaled down (and some extra additions even, in that particular case)).
I'm sure they can, but ATI has parts in the mainstream segment as well, and the relative yields/price/performance ratios are still going to be in their favor, regardless of how nvidia decides to scale their architecture. Basically, at any given performance point, the GF100 part will probably be more expensive to *make*, just like the G200 vs R770 situation.
You can do many more things with the GF100, and it's use in HPC seems pretty awesome, but for mainstream gaming and consumer use, the market needs can't be met at the same price points without accepting a lower margin. That's generally not a good thing to do if you want to be competitive in that market.