Another thought: what the hell happens if a couple of months from now, actor man is being accused of being a sex pest? Or maybe he used the N word in a tweet. Or maybe he didn't quite wanna murder Donald Trump or at the very least move to Canada because of him God knows it happened before.
All things virtual actors do not have to worry about so much. Worst thing that can happen is you have to replace a voice actor.
Because the upside of having a powerful recognized brand exceeds the risk. A couple millions people might know about cyberpunk, billions of people will recognize Keanu Reeves. Cyberpunk isn't going to make the news or newspaper without Keanu Reeves or some other big name. Getting people to actually think about the game is a lot of the battle.
Ps. Keanu should move back to Canada, rec hockey teams always need a goalie.