I might have missed something, but did anyone here claim vaccinated people can't be infected?Not in relation to the using the data to consider whether vaccination prevents people getting infected.
I might have missed something, but did anyone here claim vaccinated people can't be infected?Not in relation to the using the data to consider whether vaccination prevents people getting infected.
Not can't, but in much reduced numbers:I might have missed something, but did anyone here claim vaccinated people can't be infected?
Case rates among the vaccinated remain high in differing populations. I think the most significant factor is how long after vaccination the AB's remain active and prevent infection, so demographics receiving the vaccine will be more resistant for the near future than those who had their vaccine some months earlier. We see in the UK numbers I posted a large parallel between the recently vaccinated <18s and lower infection rates, while the 40-49s who had their 2nd doses in the summer fair no better than the unvaccinated (statistically much worse but caveats apply).The virus 'circulates' mostly among the unvaccinated. Without that factor there would be less breakthroughs. So instead of 20% of the population having 80% of the covid you could have the vaccinated (100%) with significantly less cases than the 80% vaccinated have now.
There's so much wrong in that summary. The scientific understanding was pretty laughable, with science constantly changing its mind. If we'd known at the beginning what we know now, things might be different. Furthermore, many of the efforts were pretty incompetent. Thirdly, dealing with anything on a global scale throws up numbers like 'millions'. If you want meaningful data, you need to process those values sensibly, such as %age excess deaths for a given age range and health profile, and then normalise that for other populations other diseases encountered to get a decent comparison - that is, how does C19 fair against other diseases with naive populations and a demographic profile that matches (so not obese or with co-morbidities that would have resulted in early death in those other populations). Fourthly, initial treatments were found to do more harm than good, with early intubation being detrimental. Doctors were surprised that patients with low blood O2 levels were actually not doing too badly and could recover.
If you can link to better numbers proving one way or the other, please do.
Thats the darn problem with the "vaccinated" vs "unvaccinated" division that have been pushed by government and the media. While science says that the vaccinated can be carriers and transmit the disease and that among the vaccinated (as well as the unvaccinated) and that many vaccinated do not develop full immunity, the measures and the selective science chosen to complement the measures ignore the whole science. Hence there is this nonsense where the measures themselves just hide a lot of issues under the rug. They use the convenient half truth narrative so that we can return back to "normal", remove any kind of responsibility from the authority (because they did the right thing in our eyes) and throw the blame on the unvaccinated.I cannot understand, why did you cut off the table.
In Germany we have almost everywhere the 2G rule: fully vaxxed or recovered (it changend last week, but it doesn't matter for my example). And there are much more vaccinated vulnerable persons than not vaccinated.
Every weekend is football. 2G means, that unvaccianted people cannot visit these games (or restaurants with 2G etc). If there (in the stadium) is an infected fully vaccinated person, so he or she can infect other fully vaccinated people in the stadium (until last week 2G meant, that there were no restrictions, no masks, no distance etc.).
So it is possible, that more vaccinated persons are infected than unvaccinated. But who cares? They are fully vaccinated.
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Is Omicron a big deal? No, at least not in the next weeks outside of southern Africa (and not South Africa). Delta is almost everywhere dominating, this could change in january/february, if you trust Christian Drosten. All you can do is to get the third shot (or your first, second...).
You mean remove the right hand columns? Because the focus is not on whether vaccines are good at preventing serious disease, but whether they reduce infection spread by reducing people's chance to contract and spread the disease.I cannot understand, why did you cut off the table.
It's the focus of the current line of discussion in this thread!So it is possible, that more vaccinated persons are infected than unvaccinated. But who cares?
behind a paywall
Molnupiravir attacks the coronavirus by triggering an accumulation of errors in the viral genome, and there have been concerns that it might alter human genes...Panellists were far less reassured about the drug’s impact on coronavirus genes. While its mutagenic effect is designed to stop the virus replicating, mutations that make it more infective or vaccine resistant are also possible. In molnupiravir’s phase II trial, 72 structural nucleotide changes to the spike protein were found in the treatment arm, compared with nine in the placebo arm.
Several of these changes were similar to those seen in major variants including delta, FDA researchers told the panel. But they stopped short of concluding that molnupiravir would increase the risk of new variants, noting that the coronavirus spike protein was already mutating in nature.
Principally because we rely on search engine results. When looking for data, that was the only info that came up for me and it was from an official source. The data should have been corrected at the time, not left as is. And that's why it's best practice to share info rather than just complain about sources and how they are (mis)used.That said, I'm surprised that the dodgy NIMS stats are still being quoted now. Thoroughly debunked back in October, but I see it wasn't mentioned in this thread. It just goes to show how a bit of misinformation can run and run, rearing its head months later...
Banging my head against a wall. No-one was talking about the impact on hospitals. It was a specific data point about a specific topic, mutation potential in infected persons. As ever, instead of actually discussing the point to conclusion and everyone settling on an agreed reality, or at least recognising the issue in the case of diverged opinions, it's just moved on to reiterating a mantra, "vaccines are good," despite preaching to the converted.A 2:1 or 3:1 ratio represents a very, very large number of hospitalisations and deaths when the majority of the population is vaccinated.
Don't leave, you made me think about that subject!Banging my head against a wall. No-one was talking about the impact on hospitals. It was a specific data point about a specific topic, mutation potential in infected persons. As ever, instead of actually discussing the point to conclusion and everyone settling on an agreed reality, or at least recognising the issue in the case of diverged opinions, it's just moved on to reiterating a mantra, "vaccines are good," despite preaching to the converted.
This debate is, IMHO, pointless and intellectually sterile. I leave you to it.
For what it's worth, I've never particularly argued we should start vaccinating people to stop the virus turning into something more serious (which it already has, possibly due to lack of available vaccination). It is one reason for vaccination but the main reason is to stop people dying in very large numbers, becoming seriously ill with life-changing results and (to a lesser degree) developing 'Long Covid' post-viral syndrome. Forgive me if I've misinterpreted what you're trying to say, but most of your arguments seem to be similar to the Covid 'minimisers' of this world who set up strawman arguments about other diseases which simply aren't comparable to the novel coronavirus pandemic which we are all living through. To the extent of quoting misleading statistics which had previously been debunked. You dismissed my comments in an earlier post about the scientific response without actually pointing out what was 'so much wrong' with them and you haven't replied to my response. Why is Covid-19 not any 'worse' than the many viruses which have been endemic for hundreds of years and cause little serious illness? Why shouldn't we vaccinate now and save millions of lives over the next few years? The alternative is surely to allow it to run rife, killing lots of old and immuno-compromised people as well as unlucky younger folk and then just hope that it doesn't mutate into something even more serious.
I personally anticipate that we (well, those in wealthy countries first of all, of course) will be having boosters for another year or perhaps two but it is perhaps only longer-term that we'll be seeing those most vulnerable having a yearly vaccination as we currently see with influenza. You'd assume further advances in treatments will appear so that Covid becomes a milder and more treatable disease in everyone else. As you appear to be worried about future immune-escape variants, note that there is already work underway to develop vaccines which target multiple epitopes. A couple of the vaccine companies are testing combined Covid/Flu vaccines as well, I believe (Moderna and Novavax, I seem to think?).
Just what level of deaths do you think we should be willing to accept rather than to vaccinate and run the risk of escape mutations down the line (which we could then develop vaccines and treatments for, of course)? If this is a thought experiment - i.e. not using vaccines which are effective at reducing death and morbidity - how would you deal with the fallout? The hospitals would quickly be overwhelmed (seen in many countries during previous waves), leaving people dying in the street and at home in large numbers. Medical staff would be ill in such numbers that they wouldn't be able to treat patients regardless of their ailment, so more deaths. Imagine how many would leave the profession following such terrible situations.
So, what would we do if we're going to 'let it rip'? Set up 'dying rooms' for palliative care for those who we couldn't treat? Police cordons at hospitals as those with dying relatives attempted to get some sort of treatment? For me, when faced with imminent disaster, it takes a unusual viewpoint to think that doing nothing in case of future disaster might be the better option.
It should be noted that it is thought most of the variants have developed in the immuno-compromised who wouldn't be alive in previous eras due to the lack of modern medical treatments. If you are advocating that we should not use vaccines for Covid-19 because of the risk of future escape variants do you also think we should also stop treating people with certain cancers or auto-immune diseases who are the most likely 'culprits' as hosts? Just a thought experiment.
Is there anything more binary that having a vaccine or not?