A sidenote to the SA data...the 40% that got positive...had MUCH milder symptoms and MUCH less need for hospitalization.
The devil is in the details
Coronavirus Pandemic (COVID-19) (SARS-CoV-2) [2020]
- Thread starter RDGoodla
- Start date
A sidenote to the SA data...the 40% that got positive...had MUCH milder symptoms and MUCH less need for hospitalization.
The devil is in the details
green.pixel
Veteran
green.pixel
Veteran
Reinfection is to be expected from Coronaviruses, as we well know, but why no analysis of the likelihood of becoming seriously ill the second time around?
This is what is never mentioned in these reports. If you are only likely to get mild symptoms the second time around, then it's a whole different ball game. You'd hope (and perhaps even expect) that the vast majority of later infections will be mild or even asymptomatic, at least when there is a broad enough level of immunity/protection in the population. If severity of confirmed reinfections are tracked, it might give us some sort of an indication of how long we will have to likely we're going to be intensively dealing with this pandemic. My guess would be that it will be a couple years at least of booster vaccines before we're confident enough that this will become a less dangerous illness. This is working on the assumption that long-term sterilising immunity won't be possible, but if it just becomes another circulating cold virus, then not so much of a problem.
This is what is never mentioned in these reports. If you are only likely to get mild symptoms the second time around, then it's a whole different ball game. You'd hope (and perhaps even expect) that the vast majority of later infections will be mild or even asymptomatic, at least when there is a broad enough level of immunity/protection in the population. If severity of confirmed reinfections are tracked, it might give us some sort of an indication of how long we will have to likely we're going to be intensively dealing with this pandemic. My guess would be that it will be a couple years at least of booster vaccines before we're confident enough that this will become a less dangerous illness. This is working on the assumption that long-term sterilising immunity won't be possible, but if it just becomes another circulating cold virus, then not so much of a problem.
Nasal spray treatment by a Canadian biotech shows promising results. Company is planning to apply for EUA in the UK and Canada:
https://www.clinicaltrialsarena.com...educes-covid-19-viral-load-uk-clinical-trail/
The active ingredient is nitric oxide.
But note that it's only Phase 2 clinical data. However if it works, it might be an alternative to monoclonal antibodies, which require infusions with some trained personnel vs. self-administered nasal spray, for early treatment.
If it does successfully reduce viral load in the upper respiratory tract, it would also reduce transmission.
https://www.clinicaltrialsarena.com...educes-covid-19-viral-load-uk-clinical-trail/
The active ingredient is nitric oxide.
But note that it's only Phase 2 clinical data. However if it works, it might be an alternative to monoclonal antibodies, which require infusions with some trained personnel vs. self-administered nasal spray, for early treatment.
If it does successfully reduce viral load in the upper respiratory tract, it would also reduce transmission.
thats laughing gas isnt it?
WhiningKhan
Regular
No, methane is the gas that makes people laugh
New data from Germany: B117 is the most dominant Sars-Cov-2 variant.
KW stands for calendar week.
green.pixel
Veteran
Interesting that there appears to be greater risk for women from this condition and also that the prevalence numbers don't appear to match up quite the same on this side of the channel.
We know that use of the contraceptive pill increases the risk of thrombosis, so I wonder if there could be some sort of link here? Alternatively, we know that women have stronger immune systems than men, so the increased risk could be down to too strong an immune response in a tiny minority of people?
If this was the case, we could end up just giving the AZ vaccine to men and older people, though for pretty much every age group, the risk of harm from the vaccine is a couple of orders of magnitude lower than from the virus itself.
I wonder if a similar signal will appear with the other adenovirus vaccines once enough doses of those have been administered?
We know that use of the contraceptive pill increases the risk of thrombosis, so I wonder if there could be some sort of link here? Alternatively, we know that women have stronger immune systems than men, so the increased risk could be down to too strong an immune response in a tiny minority of people?
If this was the case, we could end up just giving the AZ vaccine to men and older people, though for pretty much every age group, the risk of harm from the vaccine is a couple of orders of magnitude lower than from the virus itself.
I wonder if a similar signal will appear with the other adenovirus vaccines once enough doses of those have been administered?
It`s Opel Astra. Or Vauxhall Astra (for people who cannot build own cars). 
It is a really strange situation here in Germany.
It is a really strange situation here in Germany.
WhiningKhan
Regular
Err, while I admit Opel Astra may cause immunologic responses to some people (I've even heard of people being allergic to Opels) I suspect its effectiveness for Covid is not great.