I'm a Xbox gamer so mine are more geared to that system, but you still might find them useful:
1Up Yours - audio - I always look forward to this one. Very funny and always over the top and full of swearing.
Covers all systems(PS2, PS3, Xbox, Gamecube, DS, and PSP)
OXM - audio - I'm a subscriber to the mag and disc. I mostly like their interviews, but love to play the 2 contests. Have yet to win.
K Rock XP of SquadXP.com - audio - I love this one. Wasn't sure about it at first. From a few young guys in Miami. Usually strays from gaming and features a lot about things going on their lives which predominate their "relationship" segments.
Always over an hour long.
Major Nelson - audio - The grand-daddy of Xbox podcasts. Not too bad, but at times can be a little dry. Usually has great interviews and guests.
Extremetech.com - audio - Very short, but it's nice to hear things going on in the PC space like Vista, CPUs, GPUS, etc. Mainly got this since I used to "know" Loyd Case and visited with him during shows like E3 etc. Really nice guy.
I'm also subscribed to OXM and 1Up Video Podcasts, but considering they're so huge to download and transport I don't really get into them. I really need a 1gig flash drive if I'm to regulary get into those.
Anyway, I subscribe to all my podcasts via iTunes and copy them to my Creative MuVo TX FM 256MB player and either play them while working or take them home and play them through XBMC MC360 on my modded Xbox.
ineffecient, thanks for the suggestions. I might check out EGM Live, though I've never read their magazine. I'm not really into Penny Arcade(not sure why, guess I don't have the time), but might if I like the podcast.
Tommy McClain