Several PC reviewers with higher-end systems noted that pushing graphics settings up made the game look a lot worse - CDPR advised them to leave the graphics settings on default and not crank up settings. DLSS is not recommended.
Have you seen the Toms Hardware performance review posted above by pharma? Here it is again:
https://www.tomshardware.com/news/cyberpunk-2077-performance-preview
You'd have to be insane not to turn on DLSS if you have the option. You are talking an almost 3x performance increase (that's not a typo) by using DLSS Quality mode at 4K with RT set to Ulta on a 3080 - 11.4FPS to 33fps. Similar gains can be seen elsewhere.
It's literally the only way to play the game at 4k with any level of Ray Tracing regardless of your hardware. They also post some comparison shots where there's minimal difference between DLSS Q and Native. And what minor differences there are, I'm pretty sure are worth the 3x performance increase!