Coronavirus Pandemic (COVID-19) (SARS-CoV-2) [2020]

digitalwanderer said:
I'm just tired, like totally wiped out. I'm too lethargic to play around on my computer and instead I take naps, that's like being too drunk to fish!
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When I had Covid back in January this year, I felt the same way. It was basically 14 days of: what's this?, I can't smell, ah it's Covid, I'm not going to let it conquer me!, yeah lets take a nap, I think I had Covid, I can smell again!, man am I lethargic and can't speak gooder....goodest...goood?...yeah, Good!...
 
nutball said:
I had COVID in late June, I'm still not right. My fatigue levels having been making work quite a challenge. I wouldn't say it's physically too debilitating, but it's certainly had an impact (I struggle to concentrate for more than an hour or so) and is different from before.

On the plus side I did get a text message from the NHS offering boosters this autumn, so that's good.
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The first time I got COVID I slept for like 7 days straight and was fine. The second time I had memory issues, problems multi-tasking, poor response times and issues with peripheral awareness.

First time I drove after getting sick, I had my GPS on and still missed like 4 turns. I can count on 2 fingers the number of times I have mistakenly ran a red light in 25 years. I did so 3 times in three months after COVID. Being preoccupied in my thoughts while driving everyday routes is something I actively avoid now.

I’ve made it a habit to play memory and math based games with the hope it stimulates and reactivates whatever I lost from the second infection. Luckily my work skills are unaffected.
 
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wco81 said:
Hospitalizations are starting to trend upwards at a steep ascent again. (Mod-edit) In the US.


BQ.1 and BQ.1.1 are getting their turns. Europe and Asia are also seeing sharp upward trends in hospital admissions. China is also easing restrictions, with a more vulnerable population.
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I edited in the US, but you state it's worldwide so not sure what clarifications are necessary. What's the source? https://ourworldindata.org/covid-cases shows mostly level for European hospitalisations:

1670441590051.png
 
There's no apparent rise here in primary-cause hospitalizations as of now. Hard to tell how China turns out...
Incidentally I had my first confirmed Covid bout about two weeks ago. 1 day really crappy feeling, but the fever subsided after that. In 5 days I was back at work, but I seem to have stuff left in my sinus and after a few days I was feeling sick again. I hope once I get the goo out it starts getting better.
 
wco81 said:
My link shows upturns for France and a few other countries.
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Were they selecting countries to make an argument? My graph is the same source showing much less of this reported spike. Uptick is presently very confined to a few European nations
 
Scientists discover why respiratory infections of all kinds are more prevalent in the winter.

In what researchers are calling a scientific breakthrough, scientists behind a new study may have found the biological reason we get more respiratory illnesses in winter. It turns out the cold air itself damages the immune response occurring in the nose.

“This is the first time that we have a biologic, molecular explanation regarding one factor of our innate immune response that appears to be limited by colder temperatures,” said rhinologist Dr. Zara Patel, a professor of otolaryngology and head and neck surgery at Stanford University School of Medicine in California. She was not involved in the new study.

In fact, reducing the temperature inside the nose by as little as 9 degrees Fahrenheit (5 degrees Celsius) kills nearly 50% of the billions of virus and bacteria-fighting cells in the nostrils, according to the study published Tuesday in The Journal of Allergy and Clinical Immunology.

“Cold air is associated with increased viral infection because you’ve essentially lost half of your immunity just by that small drop in temperature,” said rhinologist Dr. Benjamin Bleier, director of otolaryngology translational research at Massachusetts Eye and Ear and an associate professor at Harvard Medical School in Boston.

“it’s important to remember that these are in vitro studies, meaning that although it is using human tissue in the lab to study this immune response, it is not a study being carried out inside someone’s actual nose,” Patel said in an email. “Often the findings of in vitro studies are confirmed in vivo, but not always.”
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www.cnn.com

Scientists finally know why people get more colds and flu in winter | CNN

A new scientific finding has uncovered why we get more viral colds, flu and Covid in winter and during cold snaps.
www.cnn.com www.cnn.com


They're not talking about antibodies or T-cells.

They're talking about extracellular vesicles or EVs.

When under attack, the nose increases production of extracellular vesicles by 160%, the study found. There were additional differences: EV’s had many more receptors on their surface than original cells, thus boosting the virus-stopping ability of the billions of extracellular vesicles in the nose.

“Just imagine receptors as little arms that are sticking out, trying to grab on to the viral particles as you breathe them in,” Bleier said. “And we found each vesicle has up to 20 times more receptors on the surface, making them super sticky.”

Cells in the body also contain a viral killer called micro RNA, which attack invading germs. Yet EVs in the nose contained 13 times micro RNA sequences than normal cells, the study found.
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Yet cold weather will cause a big drop in the number of EVs available to fight off infection.

So guess what, masks help keep noses warmer and thus, likely keep higher levels of EVs than otherwise. Argument for masking more in winter months (besides the fact that covid infects better in the winter), maybe even outside.
 
Thing is, the incentives for them would be to let a lot of old people die, because they have a big demographics problem as a result of the one-child policy.
 
Interesting study which seems to indicate that one of the available theraputics, Molnupiravir, doesn't seem to help a great deal in reducing hospitalisation or deaths. Perhaps not a huge surprise as I seem to recall that a lot of commentators were unimpressed with the original trial data for the drug. That only really leaves us with the Pfizer drug, Paxlovid, as anything which seems particularly efficaceous at keeping people out of hospital? That's not great news, especially if a variant with more severe outcomes in people with prior immunity (vaccination/infection/both) emerges. Might be a good time to manufacture a lot of the stuff, just in case.

Edit: Forgot to include the link to the report!

www.theguardian.com

Pill for Covid does not reduce risk of hospitalisation or death, UK study finds

Oxford University’s Panoramic trial suggests molnupiravir can speed up recovery in vaccinated but vulnerable patients
www.theguardian.com www.theguardian.com
 
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Podcast compares how Taiwan transitioned out of Zero Covid and how China is transitioning.

www.economist.com

The World Ahead 2023 | The Economist

Future-gazing analysis, predictions and speculation
www.economist.com www.economist.com

Taiwan pushed vaccinations, using mRNA vaccines, which Chinese claim is a national security issue for them.

Taiwan increased ICU capacity and educated its populace on staying home for mild cases, not coming to hospital.

Taiwan did all the prep work for months, even years.

China was locking down people to suppress outbreaks but for all the coercive measures they use on their populace, they didn't try to force vaccinations, including boosters.

In 2020 and 2021, Xi was boasting about the People's War vs. Covid, how much better they're doing than the West. Dumb boast because he's now having to eat those words.
 
wco81 said:
Podcast compares how Taiwan transitioned out of Zero Covid and how China is transitioning.

www.economist.com

The World Ahead 2023 | The Economist

Future-gazing analysis, predictions and speculation
www.economist.com www.economist.com

Taiwan pushed vaccinations, using mRNA vaccines, which Chinese claim is a national security issue for them.

Taiwan increased ICU capacity and educated its populace on staying home for mild cases, not coming to hospital.

Taiwan did all the prep work for months, even years.

China was locking down people to suppress outbreaks but for all the coercive measures they use on their populace, they didn't try to force vaccinations, including boosters.

In 2020 and 2021, Xi was boasting about the People's War vs. Covid, how much better they're doing than the West. Dumb boast because he's now having to eat those words.
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I do find it interesting that people around my age (40's) and people around my parent's age (70-80's) that have received the Covid shot and boosters have either died or gained a strange health anomaly that's nowhere to be found in a family tree. For instance, my co-worker's husband got his second Pfizer shot and died suddenly in his sleep. Turns out it was a brain aneurism that got him. I didn't think anything about that until I remembered my dad developed an aneurism in the front of his brain and he receives multiple CTScan's a year due to cancer. My dad has had all of his "shots" and the boosters, though his was Moderna (I think).

The charts and graphs showing correlation shouldn't be written off in my opinion, because those saying "correlation doesn't mean causation" are either repeating lies to quell fear of the medicine or demonize free thinking people who don't mind thinking outside of the box. Either way.....I have many more examples of real life harm and deaths outside of my examples. I just hope people make the correct decision for themselves.
 
linthat22 said:
The charts and graphs showing correlation shouldn't be written off in my opinion, because those saying "correlation doesn't mean causation" are either repeating lies to quell fear of the medicine or demonize free thinking people who don't mind thinking outside of the box.
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From the pov of the drug manufacturer, they would need to take such correlations into account of corse, because you wouldn't want the risk of causing some severe side effects. Even if they are not sure whether they do or not.
But the "saying" is of course correct, simple correlation alone offers no proof (but also no refutal as well).
 
I do find it interesting that people around my age (50's) and people around my parent's age (80-90's) that have received the Covid shot and boosters have neither died or gained any strange health anomaly. All people I know who died or were seriously sick hadn't been vaccinated. And I won't draw any conclusion based on my experience alone because I love science and know a single point proves nothing :)

I think that after billions of people having been vaccinated if there was a vast amount of serious side effects we would already know (I doubt a World conspiracy would not be able to hide that).
 
Laurent06 said:
I think that after billions of people having been vaccinated if there was a vast amount of serious side effects we would already know (I doubt a World conspiracy would not be able to hide that).
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Massive censoring on the subject, uni-dimentional dissemination of information from the official sources & and ridiculing anyone raising concerns on the matter certainly doesn't help alleviate any doubts though
 
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