Meh... The only "new" thing about Resistance that i can see is the weapons. Some of them are really cool, and i'm sure we haven't seen them all. Looking at Insomniac history, they can really come up with some crazy weapons (Ratchet & Clank games), and if they use their imagination for Reistance the same way they did for R&C, it will be fun.
Even then, that's not exactly "new", the dynamic of the game will be the same as any FPS ever released. Run shoot strafe shoot shoot run run. 40-player online is not "new", it's "more".
With GOW we have the "cover" thing, and the game is generally presented in a different, more over the top way. Game dynamics have been done before, and presentation-wise, i don't think that should be a factor in the discussion we're having, which is about "new" game genres.
Personally, i wouldn't argue over what game has more "new" stuff with these two examples. Anyone looking for something "new" is seriously looking in the wrong shelf.