Is there an app to set your desktop to greyscale?

Not that I know of, but you could always just cheat and use your color calibration tools to wipe 'em out.

That or you could cheat and use a hardware hack, buy a B&W monitor... ;)
 
if you have an ati graphics card you could use the profile system to turn down the color levels and link it to an executable. i've never tried it myself, but it should be possable.
 
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