Just ran into my first two bugs last night. I got the one during The Rescue where your little bastard child gets zombified and stuck in the corner and won't follow you out.
Then I went back to the house to execute the mother and she had mysteriously changed from a weapons dealer to a gifts dealer. That did nothing to improve her chances of living, by the way.
On another note, I found it interesting that reading the reviews for Knothole Island (which I just started.. completed the quest to make it rain), nobody really mentioned the emphasis on puzzles.
I "finished" Fable II without encountering any real puzzles, it was only when I started to back through I hit some side quests with those silly switches you have shoot, etc.
I guess they figure combat with maxed characters isn't much of a challenge so they have to do something, and what they've chosen is puzzles. Is the 'See the Future' expansion mostly puzzle based as well?