like the 6600 XT, the non-XT version is limited to PCIe 4.0 x8 bandwidth. So when installed in a PCIe 4.0 system this is a non-issue, but performance related problems could arise when installed in a system that only supports PCIe 3.0, which currently is most systems.
This is because when using PCIe 4.0, the RX 6600 series connects to the CPU using a 16GB/s link which is sufficient for modern graphics cards as that's what you get with PCIe 3.0 x16. However, when limited to an x8 interface, the bandwidth for a PCIe 3.0 system is reduced to just 8 GB/s, and we found in the past this can heavily limit performance, especially when fetching data from system memory.