The dual-core Penryns are a much different beast than the quads.
I came from an E8400, and I'll tell you this: If you have a motherboard that's good for ~525-550 FSB, then I'd suggest buying the E8200 chip instead.
The E8200, E8400 and E8500 all overclock to pretty much the same end: somewhere between 4.0 and 4.3Ghz. The only (obvious) difference is the FSB speeds... The average overclock (to me) seems to be around 4.2Ghz -- that's 525FSB on the E8200, 467FSB on the E8400, and ~442FSB on the E8500.
Bottom line is this: The E8500 really isn't worth it, at all. The E8400 is gonna be easier on a "lower end" motherboard, but hell most P35's will do 500+FSB without blinking. So if you've got a decent P35 or X38 chipset, go for the E8200 and start loving your FSB.
Oh, and at which point, 1066 ram would make sense :
Thank you, that helped me to understand the situation between the different dual core CPUs in o/c mode.
One of the questions still spinning in my mind is if the o/c is all worth it. Do not games top out by the CPU at 3Ghz or so? So between 3-4ghz the performance increase is negligible? That always brings me back to "why not get a quad core then" with its benefits and ability to also reach well into 3Ghz. They won't do 4Ghz, sure, but does it matter?
http://techreport.com/articles.x/14573
The above performance review shows quite clearly how well the E8400 and E8500 do, but the Q9450 for instance and Q9300 stay right with it, only falling behind in minor instances, while pulling ahead big time in many applications (I don't count the synthetic stuff). For games it remains relatively flat, with the Q9xxx pulling ahead in one major instance, but never falling behind significantly in any others. This also takes into account the overclock page as well.
Only real problem I see with a Q9450 or higher... price. Some might suggest heat (at least with the Q6xxx, not the Penryn's so much) or power usage, but that's yet another reason to get the Penryn series. I'm not too worried about power usage differences anyway as it isn't that big of a deal, unless it adds up to cost me an extra xx bucks or more a month or something that might be worth scoffing at. What does an ultra clocked E8xxx burn on watts vs. a o/clocked Q9xxx anyway? Since the E8xxx can do more, the wattage gap may close too.
When considering a processor I personally want to look at everything I will be doing. I won't be playing games but also doing some rendering on 3DSmax, editing games via map editors, and running a lot of multi-tasking background programs at the same time. Games will be huge, but as this review states getting a Quad-core is just as good.
What we need are reviews for Quad-cores that actually show systems with multi-tasking environments, not just multi-threaded environments. If in the end Quad-cores don't do much difference here, than my money may rest on the E8400.