Depends on game, though prefer quality typically
In most circumstances I try to achieve 60fps as it's usually just a better gaming experience. However, depending on the game, I will sacrifice frame rate for AA for example. I despise aliasing and will try to find a good balance of high game settings and framerate to achieve desired visuals and gameplay experience.
I game at 2560x1080 ultrawide so it's not super-high resolution. Until very recently I was gaming on a 970 and had pretty much given up on buying newer games as I didn't want to play at 15-30fps but didn't want to play on low-medium settings. Again depends on the game of course. Now that I have a 1080, I'm once again able to play at stable 60fps on high-ultra settings with decent AA.